Each film-coated, single tablet of demeclocycline contains demeclocycline hydrochloride in 150 mg or 300 mg equivalents. Other inactive ingredients consist of alginic acid, corn starch, ethylcellulose, hypromellose, magnesium stearate, polyethylene glycol, and microcrystalline cellulose.
It is used in the treatment of several infections caused by susceptible strains of various bacteria. such as Rocky Mountain fever, scrub typhus, Q fever, and tick fever. Lower respiratory tract infections, such as pneumonia, Chlamydia trachomatis infections, psittacosis, relapsing fever, chancroid, bartonellosis, urinary tract associated infections, and skin infections.
A mild to moderate range of side effects has been noted. Such as nausea, vomiting, and diarrhea. diarrhea, glossitis, dysphagia, inflammatory lesions, and an increase in liver enzymes Other side effects include maculopapular rash, erythema multiforme, urticaria, and edema.
To be prescribed cautiously in patients with a previous history of central nervous system-related disorders In cases of superinfection in patients with hepatic failure, not to be prescribed during pregnancy.
This medication is not recommended for patients who have a history of hypersensitivity to any of the tetracyclines.
Dosage and administration
The usual daily dose for adults is four divided doses of 150 mg, taken orally 12 hours after meals. And a dose of 300 mg is to be given in two divided doses per day, orally, every 12 hours.
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