A single dose of this drug is available in injection and tablet dosage forms, with injections containing 500 mg per vial of Chlorothiazide equivalent, and tablets containing 250 mg of Chlorothiazide USP equivalent.
Usage of this drug is indicated in the treatment of moderate-to-severe ranges of hypertension and is used in the treatment of edema to prevent excess fluid retention in body tissues and to treat edema in cases related to hepatic and renal disorders, congestive heart failure, and swelling in the hands or feet.
A mild to moderate range of side effects has been observed. Side effects such as nausea, dizziness, fatigue, headache, abdominal pain, vomiting, and in some cases, severe dizziness, weakness, dry mouth, yellowing of the eyes or skin, dark urine, urticaria, unusual tiredness, itching, or swelling.
This medication is to be prescribed cautiously in patients with systemic lupus erythematosus, an imbalance of any electrolytes such as sodium, potassium, or magnesium, or in cases of severe dehydration or vomiting.
This medication is contraindicated in patients with a history of hypersensitivity to chlorothiazide or any of its other constituents, anuria, severe hepatic disorders, Hepatic failure occurs in cases of Addison’s disease, hypercalcemia, increased amounts of triglycerides in the bloodstream, hypokalemia, hyponatremia, hypomagnesemia, hypercholesterolemia, end-stage renal diseases in cases of stages 4 and 5, autoimmune diseases such as systemic lupus erythematosus.
Dosage and administration
In adults, the usual dosage as a diuretic consists of 10–20 mg to be administered orally once a day, post meals. The dosage should not exceed 1000 mg per day.
We have also established roots and begun this new venture in other countries as well, such as Turkey, North Korea, Myanmar, Grenada, Ghana, and Gabon.